This week's NF is the shank boss in Rasputin's lab, which is the hardest strike I've done in TTK. We beat him last evening after wondering whether we could... To help make this week's NF challenging, there's the "trickle" (supers build slowly) and void burn modifiers.
One or more bubble Titans are important, both to get past the oh so fun Warsat sequence in the beginning and especially at the really busy boss shank fight. I was a Sunsinger, and it came in handy a time or two.
I tried a year-one Atheon's Epilogue at 170, but it wouldn't touch the enemies. I settled on using a kinetic scout primary - Boolean Gemini, a void shotgun/fusion and a void machine gun - all of them as high an impact value as I had (~280-290). Rockets can't be used in the shank fight (too close).
Begin the shank fight with supers up, full heavy ammo and a synth ready. Pop a bubble when he emerges from the floor hatch, then all of you pour on machine gun fire when he begins taking damage. He goes down about as fast as the Servitor god in PoE does in a Gjallarhorn swarm. Do it fast, cuz the room begins filling with bad stuff as time passes.
On edit... The Shank can shoot through a bubble. We set up shop on the far wall behind the cylinder (near the smokey pool). The cylinder provides some cover. The bubble keeps you safer from all the ads and gives you blessing of light.